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Its primary sequence is Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2

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Petrella C, Di Certo M, Gabanella F, Barbato C, Ceci F, Greco A, Ralli M, Polimeni A, Angeloni A, Severini C, Vitali M, Ferraguti G, Ceccanti M, Lucarelli M, Severi C, Fiore M (2021) Mediterranean diet, brain and nuscle: olive polyphenols and resveratrol protection in neurodegenerative and neuromuscular disorders

These small trials have raised some concerns about the use of GLP-1RAs, but given the results from the CVOTs discussed above, current guidelines summarize GLP-1RAs as a treatment option in patients with T2D and heart failure with proven safety (49)